The percentage that reaches systemic circulation intact is estimated to be quite low, though exact figures for GHK-Cu specifically aren't well established in published literature
But if untreated, it may lead to symptoms such as: Weakness, tiredness, or lightheadedness Heart palpitations and shortness of breath Pale skin A smooth tongue Constipation, diarrhoea, loss of appetite, or gas Nerve problems like numbness or tingling, muscle weakness, and problems walking ( late signs of low B12/folate) Vision loss Mental problems like depression, memory loss, or behavioural changes Vitamin B12 is naturally present in foods of animal origin, including: In addition, nutritional yeasts contain readily available sources of vitamin B12 that have high bioavailability
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egg yolks, fish, dairy, and grain
Your natural peptide production will decline with age and during stressful periods